Senior researchers

Research focus on cellular pathways with special emphasis on autophagy, neuro­inflammation, and anti-viral immune pathways, using induced pluripotent stem cells derived from patients with dementia to generate neurons, brain organoids, and microglia.

Serves as national coordinator and PI for observational and intervention clinical trials mainly in hereditary neurodegenerative disorders. Main research interest is genotype-phenotype correlations and molecular mechanisms in neurodegenerative disorders.

Main research areas include norming, validation and development of neuropsychological tests and brief case-finding instruments and epidemiological modelling of the potential for reduction of dementia risk.

His research focuses on clini­cally affected and presymptomatic CHM P2B gene mutation carriers from the Danish FTD-3 family.

Main research focus is molecular and genetic biomarkers for diag­nosis and prognosis of neurodegenerative diseases as well as for response to interventions.